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Associate Research Scientist - qPCR and Genotyping expert

As an Associate Research Scientist in the Clinical Genetics and Genomics Group you would be an expert in qPCR and Genotyping to support an industry leading pipeline across all active therapeutic areas, with a focus on Oncology and Immunoscience. The group is responsible for the application of genetics and genomics technologies for measurement of specific genetic or genomic endpoints in clinical studies which support 1) mechanism of action hypotheses, 2) pharmacokinetic/pharmacodynamic evaluations, and  3) patient stratification or 4) novel biomarkers related to clinical response. You would liaise closely with the NGS core laboratories in Discovery to ensure the implementation of the appropriate genetic and genomic assays in early clinical studies (single genes, panels, etc) based on results of biomarker discovery efforts in those functions.  As a champion of PPD's mission to help our customers deliver life changing therapies, you strive to generate high-quality, actionable data. Job duties: o Implements data processing and analysis workflows, bioinformatics pipelines, and data storage procedures in collaboration with internal and external multidisciplinary teams. o Effectively manages available resources, distributes assignments and delegates workload as needed to achieve timely execution of projects, works with cross functional teams (internal and external teams) to execute plans and set deliverables. o Serves as a subject matter expert for qPCR and Genotyping  and data management to address a specific need. o Educates laboratory staff and/or contractors, conducts hands-on training, and delivers internal and external presentations. o Learns various NGS platforms, stays on the top of the scientific and technical innovations, and follows new trends and developments in genomic technologies to uphold client's competitive advantage. o Actively participate in internal/external collaboration, portfolio management groups and clinical study and biomarker execution teams. When you work with PPD, you are working with world-renowned scientists, state-of-the-art technologies, industry leaders with vision and therapeutic experts. Qualifications  Education and Experience: Bachelor'sdegree or equivalent and relevant formal academic / vocationalqualification Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 6+ year) or equivalent combination of education, training, & experience.  OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 4+ year) OR PhD and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 2+ year)  Knowledge, Skills and Abilities:  Knowledge of general chemistry and separation science Demonstrated Expert ability in qPCR Demonstrated Expert ability in Genotyping Next Generation Sequencing (NGS) Preferred. Ability to independently perform root cause analysis for method investigations Proficiency on technical operating systems Proven problem solving and troubleshooting abilities Proven ability in technical writing skills Time management and project management skills Good written and oral communication skills Ability to work in a collaborative work environment with a team Ability to train junior staff Working Conditions Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment. Occasional drives to site locations, occasional domestic travel.  Exposure to biological fluids with potential exposure to infectious organisms. Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste. Personal protective equipment required such as protective eyewear, garments and gloves.  Exposure to fluctuating and/or extreme temperatures on rare occasions. Physical Requirements Ability to work in an upright and /or stationary position for 6-8 hours per day.   Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment.   Occasional mobility needed. Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.     Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs. Ability to access and use a variety of computer software developed both in-house and off-the-shelf. Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences. Frequently interacts with others to obtain or relate information to diverse groups.   Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals.  Requires multiple periods of intense concentration. Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence.  Ability to perform under stress.  Ability to multi-task.   Regular and consistent attendance. 149697
Salary Range: NA
Minimum Qualification
5 - 7 years

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