Research Investigator

We are seeking a highly motivated and innovative scientist to drive the development and implementation of immunoassays broadly supporting multiple therapeutic areas including Immuno-oncology, Immunology and Fibrosis. Applicants must have a deep scientific and technical understanding of immunology and cell-based assay techniques to develop high-throughput, cell-based screening assays in in vitro/ex vivo models for lead optimization across early and late stage discovery programs. Further, the candidate will be required to bring strategic insight into program support ensuring robust and innovative solutions and approaches towards the development of high throughput immunological assays. Expertise is required in cell signaling and cell imaging. High content imaging expertise is a plus. The incumbent should possess strong collaborative and written/verbal communication skills and a positive attitude to interact with multiple stakeholders (e.g. therapeutic area teams, Chemistry and Biology leads and outside vendors). He/she should demonstrate personal leadership within the group, scientific leadership both at the bench and at data analysis, and be adept at multi-tasking.
Position Requirements/Key Responsibilities
  • Ph.D. in immunology, tumor immunology or cell biology is required with a minimum of 1-2 years post- doctoral experience
  • A strong publication record in immunology and or/tumor immunology is required.
  • Proven expertise in immune signaling and profiling readouts (proliferation, cytokine release, cell signaling/phosphorylation, biomarker analysis) in primary immune cells and co-culture systems
  • Hands-on experience with multi-parametric flow cytometry, imaging cytometry, high-content imaging and other relevant multiplexed immune based methods is a required.
  • Hands-on experience with data analytics for biomarker profiling is a plus.
  • A strong desire to succeed in cross functional teams to establish productive collaborations is critical.
  • A demonstrated excellence in both written and oral communication is essential.
  • Assist in building the necessary infrastructure for primary-cell based screening readouts/platforms (informatics, instrumentation and data analytics)
  • Build and maintain a "cutting edge" awareness of new technology advances and scientific knowledge in the field for application to discovery program support
  • Responsible for developing compelling scientific presentations and reports for internal review meetings and scientific journals.

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